ABSTRACT
beta-Coronavirus(beta-CoV) contains a type of related viruses that can cause human respiratory infections.It is widespread in nature and can cause serious harm to humans or animals. The infection of the virus has the characteristics of high infectivity, wide epidemic, strong suddenness, and without effective preventive medication, which imposes a large medical burden on the country and patients. This review briefly summarizes the epidemic situation, transmission route, pathogenicity, pathogenesis and latest progress in drugs and vaccines of acute respiratory syndrome coronavirus(SARS-CoV), Middle East respiratory syndrome coronavirus(MERS-CoV) and the severe acute respiratory syndrome coronavirus 2(SARS-COV-2) since December 2019.
ABSTRACT
β-coronavirus (β-coronavirus, β-COV) is a kind of related viruses that can cause human respiratory infections. It exists widely in nature and can cause serious harm to humans or animals. The virus infection has the characteristics of high contagiousness, wide epidemic, strong suddenness and no effective preventive medicine, which has caused a large medical burden on countries and citizens in the world. This article mainly focuses on severe acute respiratory syndrome coronavirus (SARS-COV) and Middle East respiratory syndrome coronavirus (MERS-COV), as well as new coronaviruses since December 2019 (Severe Acute Respiratory Syndrome Coronavirus 2, SARS-COV-2) The epidemiological profile, transmission route, pathogenicity and pathogenic mechanism, drugs and vaccines and other latest developments are reviewed, aiming to better prevent and control highly pathogenic The human coronavirus provides the basis.